2&8 at the B40. Slot receiver A88 is positioned to the right side of the formation. Just before the snap he starts in motion toward the left side of the field. After the ball is snapped he goes down field and, at the B33, blocks Safety B22 below the waist toward the sideline he started his motion from. Running back A15 is tackled at the B30.
Ambiguous information. Even assuming the block was not toward his own goal line, we don’t know where he was at the snap. If we assume he was still to the right of the snapper, then his block was toward his adjacent sideline, thus, legal. A, 1/10, B-30, 40 (running)/RFP.
However, if he was to the left of the snapper, then his block was away from his adjacent sideline and illegal. The foul was behind the end of the related run; so, penalize 15 yards from the spot of the foul. The distance penalty leaves the ball behind the line-to-gain, so repeat the down. A, 2/16, B-48, 25/RFP.